Experience Summary
Innovative, team-oriented R&D Scientist with experience in Organic Chemistry and specialized experience in process development and GMP/GLP manufacturing. Offers advanced Organic Chemistry laboratory and purification skills, complemented by strengths in troubleshooting, problem-solving, and interpersonal communication. Depth of expertise includes:
• Process development and optimization of compound synthesis methods.
• Fabrication and development of organic molecules with a variety of synthetic routes.
• GLP / GMP regulatory guidelines and preparation of SOPs, protocols, and reports.
• Method development for scaling-up from Micro-scale to Kilo-scale.
• Proficiency in Gas Chromatography-Mass Spectrometry, Nuclear Magnetic Resonance, High Performance Liquid Chromatography, Preparatory Chromatography, and FT-Infrared Spectrometry.
PROFESSIONAL EXPERIENCE
ALBANY MOLECULAR RESEARCH INC., SYRACUSE, NY 2012 to 2014
Research Scientist 1
Synthesis and purification of known and new chemical compounds including analysis of structure by NMR, HPLC, and GC-MS.
• Maintained records of scientific experiments and observations and submitted periodic reports based on experimental data.
• Modified reaction conditions for optimal yield and purity.
• Exhibited safe laboratory practices and appropriate chemical disposal protocols.
OSWEGO COUNTY OPPORTUNITIES/HORIZON HOUSE, OSWEGO, NY 2009 to 2012
Youth Worker
Supervised youth with special needs, counseling, and family support.
• Provided direct care of adolescents with behavioral and mental health issues.
• Taught living skills directly related to adolescent development.
• Completed daily documentation of youth activities, issues, and developments in their ongoing cases for staff communication as well as oversight and review.
STATE UNIVERSITY OF NEW YORK AT OSWEGO, NY 2009 to 2011
Teaching Assistant, Undergraduate Organic Chemistry
Supervised and instructed undergraduate students in laboratory techniques and reactions of Organic Chemistry.
• Offered instruction of undergraduate students in established lab procedures with an emphasis on exploratory learning.
• Performed weekly grading of lab reports, recording of grades, and pre-lab tests while maintaining organized records and paperwork.
NED E. KARCICH Page 2
OSWEGO HOSPITAL BEHAVIORAL SERVICES, OSWEGO, NY 2000 to 2007
Mental Health Therapy Aide
Direct patient care with a host of mental health issues.
• Completed daily documentation of client mental health symptoms and progress.
• Delivered a Regular Group therapy schedule with positive feedback from both staff and clients.
• Established Therapeutic Crisis Intervention training for employees by TCI certification which resulted in a remarkable reduction of physical restraints and resulting injuries.
RESEARCH EXPERIENCE
DEPARTMENT OF CHEMISTRY, STATE UNIVERSITY OF NEW YORK AT OSWEGO
Graduate Research Assistant, Dr. Joseph LeFevre, (Dec 2011 to Jul 2012).
Isolation and purification of natural product Betulin. Chemically modified Betulin into biologically active precursors. Coupling bioactive precursors to ß-amino acids for SAR studies and increase blood solubility.
Undergraduate Research Assistant, Dr. Fehmi Damakaci, (May 2009 to Dec 2011).
Synthesize Pterocellin derivatives for intercalcating studies. Total synthesis using a convergent synthetic strategy. Addition of ligands for increasing blood solubility and bioactivity.
EDUCATION
Masters of Science (MS), Chemistry, Earned 34 credit hours towards degree
State University of New York at Oswego, NY
Bachelor of Arts (BA), Chemistry, State University of New York at Oswego, NY
Bachelor of Arts (BA), Psychology, State University of New York at Oswego, NY
SKILL SUMMARY
Process Chemistry: Process Optimization, Route Scouting, Technical Transfer, GLP / GMP manufacturing,
Separation Techniques: Chromatography, Crystallization, Distillation, Combiflash preparatory chromatography
Analytical Techniques: HPLC, GC-MS, LC-MS, FT-IR, NMR, TLC, and other analytical equipment
Information Technology: Chemistry databases: Scifinder; Chemdraw; Microsoft Office (Word, Excel, PowerPoint, Outlook)
Educational: Adolescent (Grades 5-10), Undergraduate Laboratory (College)
Therapeutic: Crisis counseling, Individual counseling, Therapeutic Crisis Intervention, Direct client care